KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
30.61
Human Site:
S377
Identified Species:
42.08
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S377
E
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S377
E
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T498
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Dog
Lupus familis
XP_543550
1017
111618
S377
E
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S377
E
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
Rat
Rattus norvegicus
NP_001129232
1015
111665
S377
E
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S377
E
K
S
N
I
H
Q
S
T
Y
G
K
S
L
A
Frog
Xenopus laevis
Q8QFR2
1013
112021
S377
E
K
N
N
I
H
Q
S
T
Y
G
K
S
L
A
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
N377
E
K
N
A
I
H
Q
N
I
Y
G
K
S
L
A
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
N377
E
K
N
S
I
H
Q
N
I
Y
G
K
S
L
A
Fruit Fly
Dros. melanogaster
O17468
1047
113397
K374
E
Q
N
A
I
I
R
K
M
Y
G
K
N
Y
V
Honey Bee
Apis mellifera
XP_001122939
838
91355
R223
G
G
T
T
H
V
L
R
L
S
W
S
P
D
G
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
F320
P
G
T
L
K
P
L
F
V
I
N
N
I
F
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
G349
D
L
S
W
S
P
D
G
Y
S
L
F
A
C
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S377
E
L
D
E
L
K
K
S
R
Y
G
D
V
R
G
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
P225
I
E
H
I
I
T
E
P
F
K
E
S
P
L
T
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
T375
V
I
A
A
Q
F
E
T
G
E
L
G
W
V
A
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
73.3
33.3
0
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
86.6
86.6
60
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
26.6
13.3
6.6
P-Site Similarity:
N.A.
26.6
N.A.
40
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
18
0
0
0
0
0
0
0
0
6
6
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
6
0
6
0
0
0
6
0
0
0
0
6
0
6
0
% D
% Glu:
65
6
0
6
0
0
12
0
0
6
6
0
0
0
0
% E
% Phe:
0
0
0
0
0
6
0
6
6
0
0
6
0
6
0
% F
% Gly:
6
12
0
0
0
0
0
6
6
6
65
6
0
0
12
% G
% His:
0
0
6
0
12
53
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
12
65
6
0
0
12
6
0
0
6
0
6
% I
% Lys:
6
53
0
0
6
6
6
6
0
6
6
59
0
0
0
% K
% Leu:
0
12
0
6
6
0
12
0
6
0
12
0
6
59
0
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
0
0
24
12
0
0
0
12
0
0
6
6
6
0
6
% N
% Pro:
6
0
0
0
0
12
0
6
0
0
0
0
12
0
0
% P
% Gln:
0
6
0
0
6
6
53
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
30
0
0
6
6
6
0
0
0
0
6
0
% R
% Ser:
0
6
42
6
6
0
6
48
0
12
0
18
53
0
6
% S
% Thr:
0
0
12
6
0
6
0
12
42
0
0
0
0
0
6
% T
% Val:
6
0
0
0
0
6
0
0
6
0
0
0
6
6
6
% V
% Trp:
0
0
0
6
0
0
0
0
0
0
6
0
6
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
65
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _